N-naphthaloyl
tethered dirhodium for Asymmetric cyclopropanation of olefins
We have interest in the high-throughput asymmetric cyclopropanation of olefins using newly synthesized
dirhodium (II) complexes in a new one pot approach directed by the in situ generation of phenyl iodonium ylides. The approach is used to access to biologically
active enantiomerically pure entities that can serve as active ingredient of a drug.
X-ray of our N-naphthaloyl tethered chiral cplx |
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Ghanem et al, Chemistry: A European Journal, 16 (2010) 3291-3295. |
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Chiral square conformation of Rh2(nttl)4 |
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Asymmetric cyclopropanation of olefins |
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Cyclopropanes in biologically active products |
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M. Gardiner and A. Ghanem, 2010, unpublished results |
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Enantioselective analysis of cyclopropanes |
M. Gardiner and A. Ghanem, 2011, unpublished results
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